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A guide to what researchers have studied and where the evidence is limited. The findings below describe specific studies or prescription formulations. They do not establish the safety or effectiveness of products in this catalog.
Retatrutide acts on three hormone receptors: GLP-1, GIP, and glucagon. In a phase 3 clinical trial, adults with obesity who received the study drug lost more weight than those who received placebo. Retatrutide remains investigational and has no FDA approval.
Tesamorelin stimulates growth hormone release. The FDA-approved prescription formulation Egrifta is indicated to reduce excess abdominal fat in adults with HIV-associated lipodystrophy. Its approval is limited to that use, and the label describes a weight-neutral effect.
Researchers have studied this mitochondrial peptide in cells and animals for its role in muscle metabolism and response to exercise. Whether administered MOTS-C improves endurance or blood sugar regulation in humans remains uncertain.
Animal studies have examined muscle, tendon, and ligament injury. Human evidence remains limited, and benefits for injury recovery or digestive tract healing have yet to be established.
Laboratory research has examined this copper peptide in collagen remodeling, wound repair, and pathways related to inflammation and oxidative stress. Human evidence for skin or hair outcomes remains limited, especially for injectable use.
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